The study aimed to examine the concept of psyche according to the Qur’an. By using content analysis in accordance with the qualitative research pattern, the Qur’an was read and themes were created. The themes are birds on the four mountains, the soul that comes with a driver and a witness, building a friendship with Satan, the soul that comes with a guardian and a observer, building a friendship with God, there is a tremendous trial from your God. In findings, fıtrat or genesis or human nature in the Qur’an means psyche. The psyche compartments are soul, spirit, heart, friend, ego. In the Qur’an, the soul is nefis. The character is the friend. The heart is the driver for the infidel’s psyche. The heart is the guardian for the muslim’s psyche. The ego is the witness for the infidel’s psyche. The ego is the observer for the muslim’s psyche. Spirit is the source of vitality and is not responsible for the trial in this world. The psyche compartments are the basis for life, death and resurrection. Therefore, they are effective in the formation of emotions, thoughts and behaviors. The psyche compartments will help us at caring, at disease diagnosis, at treatment and in understanding of the human.